Thyroid hormones are the only known biologically active substances that contain iodine. They have two important functions: in a growing organism they are necessary for normal development, especially of the central nervous system, and in adults they are responsible for regulating metabolism, acting on almost all organs and tissues, regulating energy expenditure, its speed and volume.
To ensure these functions, the thyroid gland contains large reserves of thyroid hormones. The metabolism of thyroid hormones occurs mainly in the liver, but is carried out partially in target tissues, for example in the brain. The level of thyroid hormones in the plasma is very finely regulated by the adenohypophysis using TSH with the participation of negative feedback mechanisms. TSH serves as a signal for the production of thyroid hormones, the main one of which is T4, which can be converted into T3 mainly in the tissues.
Thyroid hormones act mainly through intracellular receptors that influence the expression of certain genes.
Purposes of use
Many patients on replacement therapy have difficulty efficiently converting levothyroxine (T4) to triiodothyronine (T3), while the body requires both hormones. This may be due to an overload of toxins in the liver or a deficiency of zinc, which is necessary for the conversion of T4 to T3. There are also other factors that can interfere with the conversion of T4 to T3, including nutrient depletion and excess iodine, which are common causes.
Due to the long-standing controversy regarding whether hypothyroid patients can be optimally replaced by treatment with T4 alone, dissatisfaction with the outcome of T4 monotherapy remains high; Numerous studies have addressed the potential benefits of combined T3 and T4 therapy. T3 added to a T4 dosage sufficient to normalize serum T4 and TSH, bringing T3 levels into at least the mid-normal range.
This compound drug based on thyroid hormone is prescribed for replacement therapy, including conditions after resection of the thyroid gland, radioiodine therapy and oncological lesions of the organ or suppressive therapy.
Replacement therapy is prescribed for hypothyroidism of any etiology:
Primary and secondary hypothyroidism, diffuse and mixed euthyroid goiter, subacute and autoimmune thyroiditis, thyroid cancer (after surgical treatment), obesity with hypothyroidism.
Dosage
Initially small doses are prescribed, with increase to the therapeutic dose in 3-4 weeks. In patients with heart disease and over 65 years of age, doses of thyroid hormones are reduced (the risk of side effects on the cardiovascular system). In children, the need for thyroid hormones increases during pregnancy. To improve adaptation to thyroid hormone treatment, adrenoblockers may be prescribed.
How to use
Basically, the dosage starts with 1 pill per day and every 5-6 days increases by 1 pill per day. And the maximum is 3 mcg pills per day. Distribute a few tablets throughout the day. The maximum cycle lasts seven weeks. At least six weeks should pass between one cycle and another. Furthermore, it will bring the thyroid gland back to normal functioning. It is commonly stacked with clenbuto to make both even more effective at burning fat.
- Average dose: 1 to 3 pills per day.
- Effective dosage: pyramid method (1-2-3-3-2-1)
- Proven cycle: 5-6 weeks
Effects
- Boost your metabolism
- Strengthen heat production
- Burning fat
- Stimulatory effect on the central nervous system
- Reduced need for sleep
- Improve physical performance
Side effects
- Tachycardia, increased blood pressure
- Agitation
- Insomnia
- Muscle tremors
- Dry mouth
- Sweating
- I’m hot
Warnings
- Please note that you will lose MUCH more muscle with Tyrois mixos without any anabolic assistance than you would with it.
Profile
- Half-life: 5-7 days
- Frequency of intake: 1-2 per day
Contraindications
- Acute myocardial infarction
- Uncorrected adrenal insufficiency
- Acute myocarditis, pancarditis
- Active cardiac arrhythmias
- Thyrotoxicosis
- Hyperthyroidism
How to store
- Keep out of reach of children
- Store in a cool, dry place, away from direct sunlight
- Store at room temperature
- Do not use after the expiry date
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