The HGH fragment (176-191) is a synthetic peptide that represents the specific short portion of the amino acid chain of HGH (amino acids at positions 176-191 of the C-terminus of human growth hormone). This very fragment of HGH is responsible for its strong fat burning properties, but it does not have as strong an impact on insulin levels as HGH does. Clinical studies confirm that, in both humans and animals, HGH fragment leads to lipolysis (breakdown of fat) and inhibits lipogenesis, where HGH fragment can be up to 12.5 times more potent than HGH to burn fat. HGH fragment 176-191 mimics the way natural human growth hormone regulates the breakdown of fat, but without the unwanted side effects on blood sugar, insulin levels, or cell proliferation.
CLINICAL TRIALS AND RESULTS OF THE HGH FRAGMENT (176-191).
The HGH 176-191 fragment has been studied mainly in animal models. While it preserves the fat burning effects of HGH, it avoids some other effects of its parent protein such as increasing IGF-1 levels, negatively impacting carbohydrate metabolism, altering insulin sensitivity or increasing growth of long bones.
A scientific clinical study published in 2013 in the Journal of Endocrinology and Metabolism evaluated 6 studies on HGH Fragment 176-191 to evaluate the rate and significance of possible negative effects associated with HGH Fragment. The results were that administration of the HGH 176-191 fragment (compared to placebo) caused no changes in glucose levels, glucose tolerance, insulin sensitivity, or IGF-1 levels. This suggests that the HGH 176-191 fragment offers numerous benefits of hGH but without its possible associated negative side effects.
HGH-FRAGMENT INHIBITS LIPOGENESIS
Similar to unmodified HGH, this truncated form of human growth hormone helps with fat metabolism and inhibits the creation of fatty acids and other lipids in the body. But HGH Fragment directly affects adipose tissue, especially adipose cells, and increases lipolytic action. Thanks to this, fat metabolism works faster and stronger than in the case of HGH, and the HGH 176-191 fragment seems to be a more suitable option for burning fat and treating obesity than the regular body hormone human growth.
POSSIBLE BENEFITS OF THE HGH FRAGMENT SCIENTIFICALLY INVESTIGATED
- Strong fat burning properties without side effects
- Stimulates lipolysis and inhibits lipogenesis
- Does not cause changes in glucose levels & tolerance, insulin sensitivity or IGF-1 levels
- HGH-Fragment can be up to 12.5 times more powerful than HGH for burning fat
- It is a more suitable option for the treatment of fat burning and obesity than regular hGH
- Increases energy levels
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