Methandienone (danabol) is a most famous and widely used steroid in sports.
The structure of Methandienone contains a 17-alpha-methyl group. It is the alkylation of C17-alpha that makes the oral use of this anabolic steroid possible, with a very noticeable effect on the body (and a negative effect on the liver).
The half-life of Methandienone is 4.5-6 hours. The drug has moderate estrogenic effects, and its conversion rate to a metabolite with more pronounced androgenic properties via the enzyme 5-alpha reductase is low. The benefits of methandienone have made it popular among bodybuilders and athletes looking to increase muscle mass and strength.
It binds to SHBG worse than other steroids, therefore, even at high rates, the steroid remains in a free state.
The manufacturing company tried to create a steroid that has a lower androgen rate than testosterone, but maintains the property of increasing muscle mass (anabolism). He did this by altering the basic chemical structure of testosterone in such a way as to change its metabolism and location in the body. With the help of the famous Dr. Ziegler, Ciba launched one of the “most effective oral anabolic steroids”. The drug was released in 1958 and is the most studied steroid after testosterone.
EFFECTS:
Promotes a rapid increase in strength and muscle mass
Improve your recovery
Increase glycogen level
Increased appetite.
Methandienone improves recovery and quickly adapts to stimuli, contributing not only to hypertrophy, but also to hyperplasia (enlargement of some organs). Along with this comes an excellent increase in muscle nitrogen retention, providing an excellent anabolic environment.
Methandienone reduces the level of glycogenolysis, i.e. the breakdown of glycogen. Glycogen, which is one of the factors responsible for muscle volume, water retention in muscle tissue, as well as energy supply to muscles, obviously, with its higher concentrations in the muscle environment, we have achieved more satisfactory results.
Methandienone is also an anabolic known to increase strength and fluid retention potential, helping to prevent joint damage that can be caused by increased strength.
Methandienone cycles usually produce results in a very short time, which is also an advantage. For example, in 4 weeks of using Methandienone, an increase of 4-6 kg is achieved. It is because of this characteristic of rapid weight gain that Methandienone can be used at the beginning of any cycle.
SIDE EFFECTS:
Increased risk of aromatization
Increased blood pressure
An increase in cholesterol levels
Androgenic side effects are possible: hair loss on the scalp, acne, suppression of the production of one’s own testosterone, etc.
Liver toxicity – manifested through alpha-17-alkylation
Myocardial hypertrophy – especially at high doses.
DOSAGE:
Methandienone is usually used initially in a cycle, as a “boot”. Average dosages for an initial Methandienone cycle are 50-60 mg per day, but for more advanced athletes, doses of 100-150 mg per day are relatively common.
Among the side effects we can highlight aromatization, which means that it can cause a significant increase in the level of female hormones during and after use.
Methandienone significantly increases dopamine levels, which has a positive effect on mood, motivation and libido.
Higher dosages of the drug (100 mg and above) make sense only when using this steroid alone, as a rule, when combined with other steroids, its dosage does not exceed 50 mg per day, even in experienced athletes .
Half-life: 6-8 hours.
Duration of action: 12-15 hours.
Frequency of intake: 3 times a day.
Hepatotoxic rate: moderate.
Converts to DHT: no.
Detection time: more than 6 weeks*
*- approximate drug concentrations at various dosages
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